Cell mediated immunity in laboratory vaccine surveillance – A tool to better predict immunity to vaccine preventable diseases?

The purpose of this review is to summarize current knowledge on cell-mediated immunity (CMI) against vaccine-preventable diseases (VPD) included – and considered to be included – in the National Immunization Program (NIP) in Sweden and, to investigate the possible added value of CMI in vaccine surveillance and in research to address knowledge gaps.

The report provides primarily an information basis for future decision-making regarding the role of CMI in the surveillance of VPD, at the Agency. It may also be of value to professionals and specialists such as managers of NIPs and managers of laboratory surveillance of NIPs, as well as national and international communicable disease control and prevention authorities and public health agencies.